Discordant Care as a Computable Phenotype: Real-Time Detection of Routine Protocol Completion Without Cognitive Patient Engagement Predicts Hospital Mortality in the ICU"

This study defines and validates "discordant care"—the completion of routine nursing assessments without documented orientation evaluation—as a real-time computable phenotype that independently predicts increased hospital mortality in ICU patients, revealing a distinct care process signal of cognitive disengagement that is invisible to current quality metrics.

Born, G.2026-02-26📄 intensive care and critical care medicine

EEG-guided early cessation of sedation and TTM in patients after cardiac arrest: a feasibility and safety study

This feasibility and safety study demonstrates that early cessation of sedation and targeted temperature management in comatose cardiac arrest patients with favorable early EEG patterns significantly reduces mechanical ventilation duration and ICU stay without increasing complications or worsening short-term neurological outcomes.

Tjepkema-Cloostermans, M. C., Beishuizen, A., Strang, A. C. + 6 more2026-02-22📄 intensive care and critical care medicine